Anti-DCTN3 antibody (ab230012)

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Overview

  • Product name

    Anti-DCTN3 antibody
    See all DCTN3 primary antibodies

  • Description

    Rabbit polyclonal to DCTN3

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant full length protein corresponding to Human DCTN3 aa 1-176.
    Sequence:

    MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSK RERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVAL LEQVNALVPMLDSAHIKAVPEHAARLQRLAQIHIQQQAPWGVGVRDEAGS LVEDVGFAQFLSVLHFGPTGPVCGNH


    Database link: O75935-2

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • IHC-P: Human pancreatic tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Together with dynein may be involved in spindle assembly and cytokinesis.

  • Tissue specificity

    Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

  • Sequence similarities

    Belongs to the dynactin subunit 3 family.

  • Cellular localization

    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cleavage furrow. Midbody. Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
  • Information by UniProt

  • Database links

    • Alternative names

      • DCNT22 antibody
      • DCTN 22 antibody
      • DCTN22 antibody
      • Dctn3 antibody
      • DCTN3_HUMAN antibody
      • dynactin 3 (p22) antibody
      • dynactin 3 antibody
      • dynactin 3 isoform 1 antibody
      • Dynactin complex subunit 22 kDa subunit antibody
      • dynactin light chain antibody
      • Dynactin subunit 3 antibody
      • p22 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DCTN3 antibody (ab230012)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DCTN3 antibody (ab230012)

      Paraffin-embedded human pancreatic tissue stained for DCTN3 using ab230012 at 1/100 dilution in immunohistochemical analysis.

    References

    ab230012 has not yet been referenced specifically in any publications.

    Publishing research using ab230012? Please let us know so that we can cite the reference in this datasheet.

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