Overview

  • Product name

  • Description

    Rabbit polyclonal to DCTN3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human DCTN3 aa 1-176.
    Database link: O75935

  • Positive control

    • IHC-P: Human skeletal muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Together with dynein may be involved in spindle assembly and cytokinesis.
  • Tissue specificity

    Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
  • Sequence similarities

    Belongs to the dynactin subunit 3 family.
  • Cellular localization

    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cleavage furrow. Midbody. Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • DCNT22 antibody
    • DCTN 22 antibody
    • DCTN22 antibody
    • Dctn3 antibody
    • DCTN3_HUMAN antibody
    • dynactin 3 (p22) antibody
    • dynactin 3 antibody
    • dynactin 3 isoform 1 antibody
    • Dynactin complex subunit 22 kDa subunit antibody
    • dynactin light chain antibody
    • Dynactin subunit 3 antibody
    • p22 antibody
    see all

Images

  • Paraffin-embedded human skeletal muscle tissue stained for DCTN3 using ab230034 at 1/100 dilution in immunohistochemical analysis.

References

ab230034 has not yet been referenced specifically in any publications.

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