• Product name

  • Description

    Rabbit polyclonal to DCXR
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-244 of Human DCXR (UniProt: Q7Z4W1).

  • Positive control

    • HepG2 whole cell lysate; Human H661 xenograft tissue.



Our Abpromise guarantee covers the use of ab154290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • Function

    Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • Tissue specificity

    Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • Involvement in disease

    Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt
  • Database links

  • Alternative names

    • Carbonyl reductase 2 antibody
    • Carbonyl reductase II antibody
    • DCR antibody
    • Dcxr antibody
    • DCXR_HUMAN antibody
    • Dicarbonyl and L xylulose reductase antibody
    • Dicarbonyl L xylulose reductase antibody
    • Dicarbonyl/ L xylulose reductase antibody
    • Dicarbonyl/L-xylulose reductase antibody
    • HCR2 antibody
    • HCRII antibody
    • Human carbonyl reductase 2 antibody
    • kiDCR antibody
    • Kidney dicarbonyl reductase antibody
    • L xylulose reductase antibody
    • L-xylulose reductase antibody
    • P34H antibody
    • PNTSU antibody
    • SDR20C1 antibody
    • Short chain dehydrogenase/reductase family 20C member 1 antibody
    • Sperm surface protein P34H antibody
    • XR antibody
    see all


  • Anti-DCXR antibody (ab154290) at 1/1000 dilution + HepG2 whole cell
    lysate at 30 µg

    Predicted band size: 26 kDa

    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human H661 xenograft tissue labeling DCXR with ab154290 at 1/500 dilution.


ab154290 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154290.
Please use the links above to contact us or submit feedback about this product.

For licensing inquiries, please contact partnerships@abcam.com

Sign up