• Product name

  • Description

    Rabbit polyclonal to DCXR
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human DCXR aa 182-244. The exact sequence is proprietary.
    Database link: Q7Z4W1

  • Positive control

    • Human kidney tissue; HepG2 whole cell lysate.



Our Abpromise guarantee covers the use of ab191369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.
IHC-P Use a concentration of 7.5 µg/ml.


  • Function

    Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • Tissue specificity

    Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • Involvement in disease

    Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt
  • Database links

  • Alternative names

    • Carbonyl reductase 2 antibody
    • Carbonyl reductase II antibody
    • DCR antibody
    • Dcxr antibody
    • DCXR_HUMAN antibody
    • Dicarbonyl and L xylulose reductase antibody
    • Dicarbonyl L xylulose reductase antibody
    • Dicarbonyl/ L xylulose reductase antibody
    • Dicarbonyl/L-xylulose reductase antibody
    • HCR2 antibody
    • HCRII antibody
    • Human carbonyl reductase 2 antibody
    • kiDCR antibody
    • Kidney dicarbonyl reductase antibody
    • L xylulose reductase antibody
    • L-xylulose reductase antibody
    • P34H antibody
    • PNTSU antibody
    • SDR20C1 antibody
    • Short chain dehydrogenase/reductase family 20C member 1 antibody
    • Sperm surface protein P34H antibody
    • XR antibody
    see all


  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling DCXR with ab191369 at 7.5 µg/ml.

  • Anti-DCXR antibody (ab191369) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 26 kDa

    12% SDS-PAGE.


ab191369 has not yet been referenced specifically in any publications.

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