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Rabbit polyclonal to DDIT3
Mouse, Rat, Human
Predicted to work with:
conjugated to KLH, corresponding to amino acids 153-169 of Human DDIT3 (with added N-terminal K).
Whole extract of growth arrested rat PC 12 pheochromocytoma cells.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.097% Sodium azide Constituents: 0.0268% PBS, 1% BSA
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. PubMed: 20683254
1/250. Detects a band of approximately 29 kDa (predicted molecular weight: 20 kDa).
Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.
Involvement in disease
Note=A chromosomal aberration involving DDIT3 is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with FUS.
Belongs to the bZIP family.
Contains 1 bZIP domain.
Information by UniProt
C/EBP homologous protein antibody
C/EBP Homology Protein antibody
C/EBP zeta antibody
This product has been referenced in:
de Graaff MA
et al. Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation. Lab Invest 96:885-94 (2016).
Read more (PubMed: 27270875) »
et al. N-acetylcysteine protects against bupivacaine-induced myotoxicity caused by oxidative and sarcoplasmic reticulum stress in human skeletal myotubes. Anesthesiology 113:560-9 (2010).
Read more (PubMed: 20683254) »
See all 3 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"