Overview

  • Product name

  • Description

    Rabbit polyclonal to DDOST
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Xenopus laevis, Zebrafish, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 230 and 456 of Human DDOST (UniProt: P39656).

  • Positive control

    • A431, H1299, HeLa and HepG2 whole cell lysates.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 51 kDa.

Target

  • Relevance

    DDOST (Dolichyl-diphosphooligosaccharide-protein glycosyltransferase) is a component of the oligosaccharyltransferase complex. This complex catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum and co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
  • Cellular localization

    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • Database links

  • Alternative names

    • Advanced glycation endproduct receptor 1 antibody
    • AGE R1 antibody
    • AGER1 antibody
    • CDG1R antibody
    • DDOST 48 kDa subunit antibody
    • Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit (non catalytic) antibody
    • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit antibody
    • Dolichyl-diphosphooligosaccharide-protein glycosyltransferase antibody
    • EC 2.4.1.119 antibody
    • KIAA0115 antibody
    • MGC2191 antibody
    • OK/SW-cl.45 antibody
    • OKSWcl45 antibody
    • Oligosaccharyl transferase 48 kDa subunit antibody
    • Oligosaccharyltransferase 48 kDa subunit antibody
    • Oligosaccharyltransferase antibody
    • Oligosaccharyltransferase subunit 48 antibody
    • OST antibody
    • OST48 antibody
    • RP23-25C1.4 antibody
    • WBP1 antibody
    • wu:fa11d01 antibody
    • zgc:66068 antibody
    • zgc:77478 antibody
    see all

Images

  • Anti-DDOST antibody (ab151978) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size: 51 kDa



    10% SDS PAGE

References

ab151978 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151978.
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