Key features and details
- Rabbit polyclonal to DDX21
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DDX21 antibody
See all DDX21 primary antibodies
DescriptionRabbit polyclonal to DDX21
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment, corresponding to a region within amino acids 101-300 of Human DDX21 (Q9NR30).
- A549, HeLa, HepG2 and HCT116 whole cell lysates.
General notesKeep as concentrated solution.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: PBS, 1% BSA, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab126968 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 87 kDa.|
FunctionCan unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing.
Sequence similaritiesBelongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
DomainThe two enzymatic activities reside in two separate domains, the helicase in the N-terminus and the foldase in the C-terminus.
The 3 X 5 AA repeats seem to be critical for the RNA folding activity.
Cellular localizationNucleus > nucleolus.
- Information by UniProt
- Ddx21 antibody
- DDX21_HUMAN antibody
- DEAD (Asp-Glu-Ala-Asp) box helicase 21 antibody
ab126968 has been referenced in 1 publication.
- Cai Y et al. Broad Susceptibility of Nucleolar Proteins and Autoantigens to Complement C1 Protease Degradation. J Immunol 199:3981-3990 (2017). PubMed: 29070672