Overview

  • Product name
  • Description
    Rabbit polyclonal to DDX3Y
  • Host species
    Rabbit
  • Specificity
    This antibody detects endogenous levels of total DDX3Y protein.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human DDX3Y (internal sequence).
    Database link: O15523

  • Positive control
    • Human brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride

    Without Mg 2+ and Ca 2+
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196663 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.

Target

  • Function
    Probable ATP-dependent RNA helicase. May play a role in spermatogenesis.
  • Tissue specificity
    Testis-specific. Expressed predominantly in spermatogonia.
  • Involvement in disease
    Note=DDX3Y is located in the 'azoospermia factor a' (AZFa) region on chromosome Y which is deleted in Sertoli cell-only syndrome. This is an infertility disorder in which no germ cells are visible in seminiferous tubules leading to azoospermia.
  • Sequence similarities
    Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localization
    Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATP dependent RNA helicase DDX3Y antibody
    • ATP-dependent RNA helicase DDX3Y antibody
    • DBY antibody
    • DDX3Y antibody
    • DDX3Y_HUMAN antibody
    • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y linked antibody
    • DEAD box protein 3 Y chromosomal antibody
    • DEAD box protein 3 antibody
    • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide Y chromosome antibody
    • Y-chromosomal antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed paraffin embedded human brain tissue labeling DDX3Y with ab196663 at a 1/50 dilution. Right image treated with synthesized peptide.

References

ab196663 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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