DEA NONOate (Diethylamine nonoate), Nitric oxide (NO) donor (ab145197)

Overview

  • Product name

    DEA NONOate (Diethylamine nonoate), Nitric oxide (NO) donor
  • Description

    Nitric oxide (NO) donor
  • Biological description

    Nitric oxide (NO) donor. Spontaneously release NO in a pH dependent manner. The half life in 0.1 M phosphate buffer, pH 7.4, is t½ = 16 min. at 22-25 °C or t½= 2 min. at 37 °C. Liberates 1.5 moles of NO per mole of parent compound. Shows central effects in vivo.

    See similar compounds
  • Purity

    > 98%
  • CAS Number

    56329-27-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(N,N-Diethylamino)-diazenolate-2-oxide diethylammonium salt
  • Molecular weight

    206.29
  • Molecular formula

    C4H10N3O2.C4H12N
  • PubChem identifier

    10176637
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 100 mM and in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC[NH2+]CC.CCN(CC)N(N=O)[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Pierrefiche O & Naassila M Endogenous nitric oxide but not exogenous no-donor S-nitroprussiate facilitates NMDA excitation in spontaneous rhythmic neonatal rat brainstem slice. Brain Res 1543:9-16 (2014). Read more (PubMed: 24183786) »
  • Foster JD  et al. Nitric oxide-mediated modulation of the murine locomotor network. J Neurophysiol 111:659-74 (2014). Read more (PubMed: 24259545) »
  • Reimann K  et al. NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery. PLoS One 8:e53655 (2013). Read more (PubMed: 23301097) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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