Overview

  • Product name

  • Description

    Rabbit polyclonal to DECR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human DECR1. (Near the C terminal; NP_001350).
    Database link: Q16698

  • Positive control

    • Human endometrial carcinoma, Human colon cancer, Human fetal liver and PC3 lysates; Human ovarian cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198848 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 36 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function

    Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
  • Tissue specificity

    Heart = liver = pancreas > kidney >> skeletal muscle = lung.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1200012F07Rik antibody
    • 2 antibody
    • 2,4 dienoyl CoA reductase [NADPH] antibody
    • 2,4 dienoyl CoA reductase 1 antibody
    • 2,4 dienoyl CoA reductase mitochondrial antibody
    • 2,4-dienoyl-CoA reductase, mitochondrial antibody
    • 4 enoyl CoA reductase antibody
    • 4-dienoyl-CoA reductase [NADPH] antibody
    • 4-enoyl-CoA reductase [NADPH] antibody
    • DECR 1 antibody
    • DECR antibody
    • DECR_HUMAN antibody
    • DECR1 antibody
    • Nadph antibody
    • OTTMUSP00000004962 antibody
    • RP23-338J24.3 antibody
    • SDR18C1 antibody
    • Short chain dehydrogenase/reductase family 18C member 1 antibody
    see all

Images

  • All lanes : Anti-DECR1 antibody (ab198848) at 1/300 dilution

    Lane 1 : Human endometrial carcinoma lysate
    Lane 2 : Human colon cancer tissue lysate
    Lane 3 : Human fetal liver tissue lysate
    Lane 4 : PC3 cell lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 36 kDa


    Exposure time: 10 seconds


    8% SDS-PAGE.

  • Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling DECR1 with ab198848 at 1/50 dilution.

References

ab198848 has not yet been referenced specifically in any publications.

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