Key features and details
- Rabbit polyclonal to DECR2/PDCR
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DECR2/PDCR antibody
DescriptionRabbit polyclonal to DECR2/PDCR
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Monkey
Recombinant fragment corresponding to Human DECR2/PDCR aa 92-242.
- A549 whole cell lysate; HeLa, HepG2 and HCT116 cells; A549 xenograft
This product was previously labelled as DECR2
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
Our Abpromise guarantee covers the use of ab153849 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 31 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionAuxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
- Information by UniProt
- 2 4 dienoyl CoA reductase 2 antibody
- 2 4 dienoyl CoA reductase 2 peroxisomal antibody
- 2 antibody
Anti-DECR2/PDCR antibody (ab153849) at 1/1000 dilution + A549 (30 µg of whole cell lysate)
Predicted band size: 31 kDa
Immunocytochemistry/ Immunofluorescence of A549 cells fixed in 4% paraformaldehyde staining DECR2/PDCR using ab153849 at a dilution of 1/500 (green). Nuclear staining with Hoechst 33342 staining.
Immunohistochemical analysis of paraffin-embedded A549 xenograft using ab153849 antibody at 1:100 dilution
ab153849 has not yet been referenced specifically in any publications.