Key features and details
- MPTP inhibitor. Potent ROS production inhibitor.
- CAS Number: 55486-00-5
- Purity: > 98%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Liquid
- Source: Synthetic
Product nameDecylubiquinone (2,3-Dmdb), MPTP inhibitor
DescriptionMPTP inhibitor. Potent ROS production inhibitor.
MPTP inhibitor. Potent ROS production inhibitor. Increases the inhibition thresholds of complex I/III, complex II/III, and complex III over oxygen consumption. Coenzyme Q10 (ab143173) analog. Shows antioxidant effects.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 100 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
The product is provided as an oil and without traces of solvents. The product has a density of 1 g/mL.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145233 has been referenced in 1 publication.
- Bajpai R et al. Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma. Nat Commun 11:1228 (2020). PubMed: 32144272