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Anti-Dedicator of cytokinesis protein 6 antibody
Rabbit polyclonal to Dedicator of cytokinesis protein 6
HumanPredicted to work with:
Recombinant fragment corresponding to Human Dedicator of cytokinesis protein 6 aa 1164-1261.
Database link: Q96HP0
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
Immunogen affinity purified
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth.
Widely expressed. Expressed at low level in spleen, cerebellum, hippocampus and in substantia nigra.
Involvement in disease
Adams-Oliver syndrome 2
Belongs to the DOCK family.
Contains 1 DHR-1 domain.
Contains 1 DHR-2 domain.
The DHR-2 domain may mediate some GEF activity.
Cytoplasm. Cytoplasm > perinuclear region. Mainly located near the cell surface.
Information by UniProt
- AOS2 antibody
- Dedicator of cytokinesis 6 antibody
- Dedicator of cytokinesis protein 6 antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dedicator of cytokinesis protein 6 antibody (ab188558)
Immunohistochemical analysis of paraffin-embedded Human liver tissue labeling Dedicator of cytokinesis protein 6 with ab188558 at 1/500 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"