Overview

  • Product name

  • Description

    Mouse polyclonal to DEFA6
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length human DEFA6 protein (NP_001917.1)

  • Positive control

    • DEFA6 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab72577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 11 kDa.

Target

  • Function

    Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.
  • Tissue specificity

    Paneth cells of the small intestine.
  • Sequence similarities

    Belongs to the alpha-defensin family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • alpha 6 antibody
    • DEF6 antibody
    • DEF6_HUMAN antibody
    • DEFA 6 antibody
    • DEFA6 antibody
    • Defensin 6 antibody
    • Defensin alpha 6 antibody
    • Defensin alpha 6 Paneth cell specific antibody
    • Defensin antibody
    • Defensin-6 antibody
    • HD 6 antibody
    • HD6 antibody
    see all

Images

  • All lanes : Anti-DEFA6 antibody (ab72577) at 1/500 dilution

    Lane 1 : DEFA6 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Developed using the ECL technique.

    Predicted band size: 11 kDa
    Observed band size: 11 kDa

References

This product has been referenced in:

  • Stronati L  et al. Altered expression of innate immunity genes in different intestinal sites of children with ulcerative colitis. Dig Liver Dis 42:848-53 (2010). WB ; Human . Read more (PubMed: 20452301) »
See 1 Publication for this product

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