Overview

  • Product name

    Deflazacort, synthetic glucocorticoid
  • Description

    Potent synthetic glucocorticoid
  • Biological description

    Potent synthetic glucocorticoid (EC50 = 13 nM). Prednisolone (ab142455 derivative. Inhibits cutaneous anaphylaxis with little effect on mast cell degranulation Shows anti-inflammatory, antiallergic and immunosuppressant effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    14484-47-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Gonzalez-Castañeda RE  et al. Deflazacort induced stronger immunosuppression than expected. Clin Rheumatol 26:935-40 (2007). Read more (PubMed: 16738843) »
  • Grossmann C  et al. Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties. Eur J Endocrinol 151:397-406 (2004). Read more (PubMed: 15362971) »
  • Latta K  et al. Effects of deflazacort and cortisone on cellular proliferation in the rat thymus. Life Sci 71:1951-60 (2002). Read more (PubMed: 12175709) »

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