Key features and details
- Rabbit polyclonal to DEGA
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DEGA antibody
See all DEGA primary antibodies
DescriptionRabbit polyclonal to DEGA
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human DEGA (C terminal).
Database link: NM_181847
Previously labelled as AMIGO2.
FormLyophilized:Reconstitute in 200ul sterile H2O.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 2% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab84416 is by a peptide affinity column.
Our Abpromise guarantee covers the use of ab84416 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
FunctionRequired for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Tissue specificityHighest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.
Sequence similaritiesBelongs to the immunoglobulin superfamily. AMIGO family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
Cellular localizationCell membrane. Nucleus. Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
- Information by UniProt
- Adhesion molecule with Ig like domain 2 antibody
- ALI 1 antibody
- ALI1 antibody
ab84416 has not yet been referenced specifically in any publications.