Overview

  • Product name

    Dehydrocorydaline chloride, AChE inhibitor
  • Description

    AChE inhibitor
  • Biological description

    Acetylcholinesterase (AChE) inhibitor. Inhibits antigen-induced histamine release from mast cells. Inhibits nicotine-induced relaxation and concomitant noradrenaline release ex vivo. Shows antiallergic and nematocidal effects in vivo.
  • Purity

    > 95%
  • CAS Number

    10605-03-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride
  • Molecular weight

    401.88
  • Molecular formula

    C22H24ClNO4
  • PubChem identifier

    160950
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=C2C=CC(=C(C2=C[N+]3=C1C4=CC(=C(C=C4CC3)OC)OC)OC)OC.[Cl-]
  • Source

    Corydalis sp.

  • Research areas

References

This product has been referenced in:

  • Dou Z  et al. Effect of wine and vinegar processing of Rhizoma Corydalis on the tissue distribution of tetrahydropalmatine, protopine and dehydrocorydaline in rats. Molecules 17:951-70 (2012). Read more (PubMed: 22258341) »
  • Matsuda H  et al. Inhibitory effects of dehydrocorydaline isolated from Corydalis Tuber against type I-IV allergic models. Biol Pharm Bull 20:431-4 (1997). Read more (PubMed: 9145224) »
  • Kurahashi K & Fujiwara M Adrenergic neuron blocking action of dehydrocorydaline isolated from Corydalis bulbosa. Can J Physiol Pharmacol 54:287-93 (1976). Read more (PubMed: 953859) »

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