Overview

  • Product name

    Anti-delta Sarcoglycan antibody
    See all delta Sarcoglycan primary antibodies
  • Description

    Rabbit polyclonal to delta Sarcoglycan
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from the C-terminal domain of human delta Sarcoglycan.

  • Positive control

    • Reconstitute with 200µl distilled water.

Properties

Applications

Our Abpromise guarantee covers the use of ab71568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/2000. Predicted molecular weight: 32 kDa.

Target

  • Function

    Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • Tissue specificity

    Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
  • Involvement in disease

    Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
    Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • Sequence similarities

    Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • Post-translational
    modifications

    Glycosylated.
    Disulfide bonds are present.
  • Cellular localization

    Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • 35 kDa dystrophin associated glycoprotein antibody
    • 35 kDa dystrophin-associated glycoprotein antibody
    • 35DAG antibody
    • CMD1L antibody
    • DAGD antibody
    • Delta-sarcoglycan antibody
    • Delta-SG antibody
    • Dystrophin associated glycoprotein delta sarcoglycan antibody
    • LGMD2F antibody
    • MGC22567 antibody
    • Placental delta sarcoglycan antibody
    • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
    • SG delta antibody
    • SGCD antibody
    • SGCD_HUMAN antibody
    • SGCDP antibody
    • SGD antibody
    see all

References

ab71568 has not yet been referenced specifically in any publications.

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