Recombinant
RabMAb

Recombinant Anti-delta Sarcoglycan antibody [EPR8706] - BSA and Azide free (ab240108)

Overview

  • Product name

    Anti-delta Sarcoglycan antibody [EPR8706] - BSA and Azide free
    See all delta Sarcoglycan primary antibodies
  • Description

    Rabbit monoclonal [EPR8706] to delta Sarcoglycan - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, IHC-P, WBmore details
    Unsuitable for: ICC
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human delta Sarcoglycan aa 200-300. The exact sequence is proprietary.

  • General notes

    Ab240108 is the carrier-free version of ab137101. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab240108 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab240108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration. Detects a band of approximately 35 kDa (predicted molecular weight: 32 kDa).
  • Application notes
    Is unsuitable for ICC.
  • Target

    • Function

      Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
    • Tissue specificity

      Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
    • Involvement in disease

      Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
      Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    • Sequence similarities

      Belongs to the sarcoglycan beta/delta/gamma/zeta family.
    • Post-translational
      modifications

      Glycosylated.
      Disulfide bonds are present.
    • Cellular localization

      Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links

    • Alternative names

      • 35 kDa dystrophin associated glycoprotein antibody
      • 35 kDa dystrophin-associated glycoprotein antibody
      • 35DAG antibody
      • CMD1L antibody
      • DAGD antibody
      • Delta-sarcoglycan antibody
      • Delta-SG antibody
      • Dystrophin associated glycoprotein delta sarcoglycan antibody
      • LGMD2F antibody
      • MGC22567 antibody
      • Placental delta sarcoglycan antibody
      • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
      • SG delta antibody
      • SGCD antibody
      • SGCD_HUMAN antibody
      • SGCDP antibody
      • SGD antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded Human heart tissue labelling delta Sarcoglycan with ab137101 at 1/100 dilution.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab137101).

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    References

    ab240108 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab240108.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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