For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome

We use cookies to make our site as useful as possible.

Our Cookie Policy explains how you can opt-out of the cookies we use.

If you continue without changing your cookie settings, we'll assume you’re happy with this.

Continue Continue

United States
Your country/region is currently set to:

If incorrect, please enter your country/region into the box below, to view site information related to your country/region.

Call (888) 77-ABCAM (22226) or contact us
Need help? Contact us

  • My account
  • Sign out
Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us
My basket
Quick order
Abcam homepage

  • Research Products
    By product type
    Primary antibodies
    Secondary antibodies
    ELISA and Matched Antibody Pair Kits
    Cell and tissue imaging tools
    Cellular and biochemical assays
    Proteins and Peptides
    By product type
    Proteomics tools
    Agonists, activators, antagonists and inhibitors
    Cell lines and Lysates
    Multiplex miRNA assays
    Multiplex Assays
    By research area
    Cancer
    Cardiovascular
    Cell Biology
    Epigenetics
    Metabolism
    Developmental Biology
    By research area
    Immunology
    Microbiology
    Neuroscience
    Signal Transduction
    Stem Cells
  • Diagnostic & Therapeutic Solutions
    Custom solutions & partnerships

    Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery.

    Create custom solutions with us

    Partner with us

  • Support
    Support hub

    Access advice and support for any research roadblock

    View support hub

    Protocols

    Your experiments laid out step by step

    View protocols

  • Events
    • Conference calendar
    • Cancer
    • Cardiovascular
    • Epigenetics & Nuclear signaling
    • Immunology
    • Neuroscience
    • Stem cells
    • Tradeshows
    • Scientific webinars
    Keep up to date with the latest events

    Full event breakdown with abstracts, speakers, registration and more

    View global event calendar

  • Pathways
    Cell signalling pathways

    View all pathways

    View all interactive pathways

Supporting our customers and employees during the COVID-19 pandemic. Read more

  1. Link

    dentt-antibody-ab168860.pdf

  1. Send me a copy of this email
    I agree to the terms and conditions.
Cardiovascular Angiogenesis Growth Factors TGF
Share by email

Anti-DENTT antibody (ab168860)

  • Datasheet
Submit a review Submit a question References (1)

Product price, shipping and contact information

Currently unavailable

Sorry, we can't display this right now.

Please contact us to place your order, or try again later.

 

Loading size & price…

 

Shipping and order information

Abpromise

Guaranteed product quality, expert customer support.

Find out more.

Western blot - Anti-DENTT antibody (ab168860)

    Key features and details

    • Rabbit polyclonal to DENTT
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-DENTT antibody
      See all DENTT primary antibodies
    • Description

      Rabbit polyclonal to DENTT
    • Host species

      Rabbit
    • Tested Applications & Species

      Application Species
      WB
      Human
      See all applications and species data
    • Immunogen

      Synthetic peptide, corresponding to a region within amino acids 643-693 of Human DENTT (NP_071400.1).

    • Positive control

      • HeLa, 293T and Jurkat whole cell lysate (ab7899).

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      pH: 7
      Preservative: 0.09% Sodium azide
      Constituent: 99% Tris citrate/phosphate

      pH 7 to 8
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Purification notes

      ab168860 was affinity purified using an epitope specific to DENTT immobilized on solid support.
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Cardiovascular
      • Angiogenesis
      • Growth Factors
      • TGF
      • Immunology
      • Innate Immunity
      • Cytokines
      • Other

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Positive Controls

      • HeLa whole cell lysate (ab150035)
      • HeLa whole cell lysate (ab29545)
      • Jurkat whole cell lysate (ab30128)
      • Jurkat whole cell lysate (ab7899)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab168860 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    WB
    Human
    All applications
    Chimpanzee
    Cynomolgus monkey
    Rhesus monkey
    Gorilla
    Orangutan
    Application Abreviews Notes
    WB
    1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
    Notes
    WB
    1/1000 - 1/5000. Predicted molecular weight: 79 kDa.

    Target

    • Function

      Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
    • Tissue specificity

      Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
    • Sequence similarities

      Belongs to the nucleosome assembly protein (NAP) family.
    • Post-translational
      modifications

      Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
    • Cellular localization

      Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.
    • Target information above from: UniProt accession Q9H2G4 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 64061 Human
      • Omim: 300564 Human
      • SwissProt: Q9H2G4 Human
      • Unigene: 136164 Human
      • Unigene: 592916 Human
      • Alternative names

        • CASK interacting nucleosome assembly protein antibody
        • CDA1 antibody
        • Cell division autoantigen 1 antibody
        • CINAP antibody
        • CTCL antibody
        • CTCL tumor antigen se20 4 antibody
        • CTCL-associated antigen se20-4 antibody
        • Cutaneous T cell lymphoma associated antigen se20 4 antibody
        • Cutaneous T cell lymphoma associated tumor antigen se20 4 antibody
        • Cutaneous T-cell lymphoma-associated antigen se20-4 antibody
        • Differentially Expressed Nucleolar TGF beta1 Target antibody
        • Differentially Expressed Nucleolar TGF beta1 Target protein antibody
        • Differentially-expressed nucleolar TGF-beta1 target protein antibody
        • HRIHFB2216 antibody
        • NP79 antibody
        • Nuclear protein of 79 kDa antibody
        • RP1 290F12.2 antibody
        • SE20 4 antibody
        • SE204 antibody
        • Testis specific protein Y encoded like 2 antibody
        • testis-specific protein Y encoded-like 2 antibody
        • Testis-specific Y-encoded-like protein 2 antibody
        • TSPX antibody
        • TSPY like 2 antibody
        • TSPY like protein 2 antibody
        • TSPY-like protein 2 antibody
        • TSPYL2 antibody
        • TSYL2_HUMAN antibody
        see all

      Images

      • Western blot - Anti-DENTT antibody (ab168860)
        Western blot - Anti-DENTT antibody (ab168860)
        All lanes : Anti-DENTT antibody (ab168860) at 0.4 µg/ml

        Lane 1 : HeLa whole cell lysate
        Lane 2 : 293T whole cell lysate
        Lane 3 : Jurkat whole cell lysate

        Lysates/proteins at 50 µg per lane.

        Developed using the ECL technique.

        Predicted band size: 79 kDa


        Exposure time: 3 minutes

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (1)

      Publishing research using ab168860? Please let us know so that we can cite the reference in this datasheet.

      ab168860 has been referenced in 1 publication.

      • Wang Q  et al. Development of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage. Sci Rep 10:12716 (2020). PubMed: 32728041

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      There are currently no Customer reviews or Questions for ab168860.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

      Get resources and offers direct to your inbox Sign up
      A-Z by research area
      • Cancer
      • Cardiovascular
      • Cell biology
      • Developmental biology
      • Epigenetics & Nuclear signaling
      • Immunology
      • Metabolism
      • Microbiology
      • Neuroscience
      • Signal transduction
      • Stem cells
      A-Z by product type
      • Primary antibodies
      • Secondary antibodies
      • Biochemicals
      • Isotype controls
      • Flow cytometry multi-color selector
      • Kits
      • Loading controls
      • Lysates
      • Peptides
      • Proteins
      • Slides
      • Tags and cell markers
      • Tools & Reagents
      Help & support
      • Support
      • Make an Inquiry
      • Protocols & troubleshooting
      • Placing an order
      • RabMAb products
      • Biochemical product FAQs
      • Training
      • Browse by Target
      Company
      • Corporate site
      • Investor relations
      • Company news
      • Careers
      • About us
      • Blog
      Events
      • Tradeshows
      • Conferences
      International websites
      • abcam.cn
      • abcam.co.jp

      Join with us

      • LinkedIn
      • facebook
      • Twitter
      • YouTube
      • Terms of sale
      • Website terms of use
      • Cookie policy
      • Privacy policy
      • Legal
      • Modern slavery statement
      © 1998-2021 Abcam plc. All rights reserved.