Anti-DENTT antibody (ab168860)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-DENTT antibody
See all DENTT primary antibodies -
DescriptionRabbit polyclonal to DENTT
-
Host speciesRabbit
-
Tested applicationsSuitable for: WBmore details
Unsuitable for: IP -
Species reactivityReacts with: Human
Predicted to work with: Chimpanzee, Cynomolgus monkey, Rhesus monkey, Gorilla, Orangutan
-
Immunogen
Synthetic peptide, corresponding to a region within amino acids 643-693 of Human DENTT (NP_071400.1).
-
Positive control
- HeLa, 293T and Jurkat whole cell lysate (ab7899).
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
-
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading... -
PurityImmunogen affinity purified
-
Purification notesab168860 was affinity purified using an epitope specific to DENTT immobilized on solid support.
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
Our Abpromise guarantee covers the use of ab168860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/5000. Predicted molecular weight: 79 kDa. |
Application notes
Is unsuitable for IP.
Target
-
FunctionPart of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
-
Tissue specificityUbiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
-
Sequence similaritiesBelongs to the nucleosome assembly protein (NAP) family.
-
Post-translational
modificationsPhosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. -
Cellular localizationNucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.
- Information by UniProt
-
Database links
- Entrez Gene: 64061 Human
- Omim: 300564 Human
- SwissProt: Q9H2G4 Human
- Unigene: 136164 Human
- Unigene: 592916 Human
-
Alternative names
- CASK interacting nucleosome assembly protein antibody
- CDA1 antibody
- Cell division autoantigen 1 antibody
see all
Images
-
Western blot - Anti-DENTT antibody (ab168860)All lanes : Anti-DENTT antibody (ab168860) at 0.4 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : 293T whole cell lysate
Lane 3 : Jurkat whole cell lysate
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 79 kDa
Exposure time: 3 minutes
Protocols
Datasheets and documents
References
ab168860 has not yet been referenced specifically in any publications.
