Anti-DENTT antibody (ab168860)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-DENTT antibody
See all DENTT primary antibodies -
Description
Rabbit polyclonal to DENTT -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: IP -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Cynomolgus monkey, Rhesus monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide, corresponding to a region within amino acids 643-693 of Human DENTT (NP_071400.1).
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Positive control
- HeLa, 293T and Jurkat whole cell lysate (ab7899).
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab168860 was affinity purified using an epitope specific to DENTT immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab168860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/5000. Predicted molecular weight: 79 kDa. |
Application notes
Is unsuitable for IP.
Target
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Function
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. -
Tissue specificity
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. -
Sequence similarities
Belongs to the nucleosome assembly protein (NAP) family. -
Post-translational
modificationsPhosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. -
Cellular localization
Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons. - Information by UniProt
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Database links
- Entrez Gene: 64061 Human
- Omim: 300564 Human
- SwissProt: Q9H2G4 Human
- Unigene: 136164 Human
- Unigene: 592916 Human
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Alternative names
- CASK interacting nucleosome assembly protein antibody
- CDA1 antibody
- Cell division autoantigen 1 antibody
see all
Images
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Western blot - Anti-DENTT antibody (ab168860)All lanes : Anti-DENTT antibody (ab168860) at 0.4 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : 293T whole cell lysate
Lane 3 : Jurkat whole cell lysate
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 79 kDa
Exposure time: 3 minutes
Protocols
Datasheets and documents
References
ab168860 has not yet been referenced specifically in any publications.
