Anti-DENTT antibody (ab168860)
Key features and details
- Rabbit polyclonal to DENTT
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DENTT antibody
See all DENTT primary antibodies -
Description
Rabbit polyclonal to DENTT -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide, corresponding to a region within amino acids 643-693 of Human DENTT (NP_071400.1).
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Positive control
- HeLa, 293T and Jurkat whole cell lysate (ab7899).
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab168860 was affinity purified using an epitope specific to DENTT immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| WB |
Human
|
| All applications |
Chimpanzee
Cynomolgus monkey
Rhesus monkey
Gorilla
Orangutan
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/1000 - 1/5000. Predicted molecular weight: 79 kDa.
|
| Notes |
|---|
|
WB
1/1000 - 1/5000. Predicted molecular weight: 79 kDa. |
Target
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Function
Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. -
Tissue specificity
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas. -
Sequence similarities
Belongs to the nucleosome assembly protein (NAP) family. -
Post-translational
modificationsPhosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. -
Cellular localization
Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons. - Information by UniProt
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Database links
- Entrez Gene: 64061 Human
- Omim: 300564 Human
- SwissProt: Q9H2G4 Human
- Unigene: 136164 Human
- Unigene: 592916 Human
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Alternative names
- CASK interacting nucleosome assembly protein antibody
- CDA1 antibody
- Cell division autoantigen 1 antibody
see all
Images
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Western blot - Anti-DENTT antibody (ab168860)All lanes : Anti-DENTT antibody (ab168860) at 0.4 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : 293T whole cell lysate
Lane 3 : Jurkat whole cell lysate
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 79 kDa
Exposure time: 3 minutes
Datasheets and documents
References (1)
ab168860 has been referenced in 1 publication.
- Wang Q et al. Development of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage. Sci Rep 10:12716 (2020). PubMed: 32728041
