Product nameDeoxycholic acid sodium salt, Ionic detergent
DescriptionWater-soluble ionic detergent for the solubilization of membrane-bound proteins.
- 3-alpha,12-alpha-Dihydroxy-5-beta-cholan-24-oic acid sodium salt
- 7-Deoxycholic acid sodium salt
- Deoxycholate sodium salt
Water-soluble ionic detergent useful for extraction of membrane receptors and other plasma membrane proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5 - 50 μM).
(3α,5β,12α)-3,12-Dihydroxycholan-24-oic acid sodium salt
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in water, 10%
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Natural - isolated from bovine and ovine gall bladder
This product has been referenced in:
- Pai R et al. Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness. Mol Biol Cell 15:2156-63 (2004). Read more (PubMed: 15004225) »