Anti-Deptor antibody (ab103298)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Deptor antibody
See all Deptor primary antibodies -
Description
Rabbit polyclonal to Deptor -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Full length protein, corresponding to amino acids 1-409 of Human Deptor (AAH12040.1).
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Positive control
- Mouse liver tissue lysate; Deptor transfected 293T cell line
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: None
Constituents: PBS, pH 7.2 -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab103298 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 46 kDa. |
Target
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Function
Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. -
Sequence similarities
Contains 2 DEP domains.
Contains 1 PDZ (DHR) domain. -
Post-translational
modificationsPhosphorylated. Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2. - Information by UniProt
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Database links
- Entrez Gene: 64798 Human
- Entrez Gene: 97998 Mouse
- Omim: 612974 Human
- SwissProt: Q8TB45 Human
- SwissProt: Q570Y9 Mouse
- Unigene: 112981 Human
- Unigene: 295397 Mouse
- Unigene: 393497 Mouse
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Alternative names
- DEP domain containing 6 antibody
- DEP domain-containing mTOR-interacting protein antibody
- DEP domain-containing protein 6 antibody
see all
Images
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Western blot - Anti-Deptor antibody (ab103298)Anti-Deptor antibody (ab103298) at 1/500 dilution + Mouse liver tissue lysate at 50 µg
Predicted band size: 46 kDa -
Western blot - Anti-Deptor antibody (ab103298)All lanes : Anti-Deptor antibody (ab103298) at 1/500 dilution
Lane 1 : Deptor transfected 293T cell line lysate
Lane 2 : non transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 46 kDa
Protocols
Datasheets and documents
References
ab103298 has not yet been referenced specifically in any publications.
