Overview

  • Product name

    Dermorphin, mu-opioid receptors agonist
  • Description

    Potent and selective agonist to μ-opioid receptors
  • Biological description

    Potent and selective natural opioid that binds as an agonist to μ-opioid receptors. 30–40 times more potent than morphine. Antinociceptive effect.
  • Purity

    > 96%
  • CAS Number

    77614-16-5
  • Chemical structure

    Chemical Structure

Properties

Images

  • Dermorphin (ab142279)

References

This product has been referenced in:

  • Mizoguchi H  et al. Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine. Peptides 32:421-7 (2011). Read more (PubMed: 21126548) »
  • Vandormael B  et al. Superpotent [Dmt¹] dermorphin tetrapeptides containing the 4-aminotetrahydro-2-benzazepin-3-one scaffold with mixed µ/d opioid receptor agonistic properties. J Med Chem 54:7848-59 (2011). Read more (PubMed: 21978284) »
  • Vandormael B  et al. Asymmetric synthesis and conformational analysis by NMR spectroscopy and MD of Aba- and a-MeAba-containing dermorphin analogues. ChemMedChem 6:2035-47 (2011). Read more (PubMed: 21990068) »

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