Anti-Desmoglein 3/PVA antibody [5G11] - BSA and Azide free (ab218851)

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Overview

  • Product name

    Anti-Desmoglein 3/PVA antibody [5G11] - BSA and Azide free
    See all Desmoglein 3/PVA primary antibodies

  • Description

    Mouse monoclonal [5G11] to Desmoglein 3/PVA - BSA and Azide free

  • Host species

    Mouse

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment within Human Desmoglein 3/PVA (extracellular). The exact sequence is proprietary.
    Database link: P32926

  • Positive control

    • IHC-P: Human skin tissue.

  • General notes

    Previously labelled as Desmoglein 3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab218851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

  • Tissue specificity

    Epidermis, tongue, tonsil, esophagus and carcinomas.

  • Sequence similarities

    Contains 4 cadherin domains.

  • Domain

    Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

  • Cellular localization

    Cell membrane. Cell junction > desmosome.
  • Information by UniProt

  • Database links

    • Alternative names

      • 130 kD pemphigus vulgaris antigen antibody
      • 130 kDa pemphigus vulgaris antigen antibody
      • Balding antibody
      • Cadherin family member 6 antibody
      • CDHF 6 antibody
      • CDHF6 antibody
      • Desmoglein 3 antibody
      • Desmoglein 3 precursor antibody
      • Desmoglein-3 antibody
      • Desmoglein3 antibody
      • DKFZp686P23184 antibody
      • DSG 3 antibody
      • DSG3 antibody
      • DSG3_HUMAN antibody
      • Pemphigus vulgaris antigen antibody
      • PVA antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Desmoglein 3/PVA antibody [5G11] - BSA and Azide free (ab218851)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Desmoglein 3/PVA antibody [5G11] - BSA and Azide free (ab218851)

      Immunohistochemical analysis of formalin-fixed paraffin-embedded human skin tissue sections labeling Desmoglein 3/PVA with ab218851 at 2 µg/mL.

    References

    ab218851 has not yet been referenced specifically in any publications.

    Publishing research using ab218851? Please let us know so that we can cite the reference in this datasheet.

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