Overview

  • Product name

    Anti-Desmoglein 3/PVA antibody [6G2C11]
    See all Desmoglein 3/PVA primary antibodies
  • Description

    Mouse monoclonal [6G2C11] to Desmoglein 3/PVA
  • Host species

    Mouse
  • Tested applications

    Suitable for: Flow Cyt, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Dog
  • Immunogen

    Recombinant fragment corresponding to Human Desmoglein 3/PVA aa 55-159. Recombinant fragment expressed in E coli
    Sequence:

    AKPCRE GEDNSKRNPI AKITSDYQAT QKITYRISGV GIDQPPFGIF VVDKNTGDIN ITAIVDREET PSFLITCRAL NAQGLDVEKP LILTVKILDI NDNPPVFSQ


    Database link: P32926

  • Positive control

    • Human esophageal and esophageal cancer tissues; A431 cells; A431 cell lysate; Human Desmoglein 3/PVA recombinant (aa55-159) protein; Human Desmoglein 3/PVA recombinant (aa55-159)-hIgGFc transfected HEK293 cell lysate.
  • General notes

    Previously labelled as Desmoglein 3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab201968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/200 - 1/400.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

IHC-P 1/200 - 1/1000.
WB 1/500 - 1/2000. Predicted molecular weight: 108 kDa.

Target

  • Function

    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • Tissue specificity

    Epidermis, tongue, tonsil, esophagus and carcinomas.
  • Sequence similarities

    Contains 4 cadherin domains.
  • Domain

    Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
  • Cellular localization

    Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • 130 kD pemphigus vulgaris antigen antibody
    • 130 kDa pemphigus vulgaris antigen antibody
    • Balding antibody
    • Cadherin family member 6 antibody
    • CDHF 6 antibody
    • CDHF6 antibody
    • Desmoglein 3 antibody
    • Desmoglein 3 precursor antibody
    • Desmoglein-3 antibody
    • Desmoglein3 antibody
    • DKFZp686P23184 antibody
    • DSG 3 antibody
    • DSG3 antibody
    • DSG3_HUMAN antibody
    • Pemphigus vulgaris antigen antibody
    • PVA antibody
    see all

Images

  • Anti-Desmoglein 3/PVA antibody [6G2C11] (ab201968) at 1/500 dilution + A431 cell lysate

    Predicted band size: 108 kDa

  • Immunohistochemical analysis of Paraffin-embedded Human esophageal tissue labeling Desmoglein 3/PVA with ab201968 at 1/200 dilution followed by DAB staining.

  • Immunohistochemical analysis of Paraffin-embedded Human esophageal cancer tissue labeling Desmoglein 3/PVA with ab201968 at 1/200 dilution followed by DAB staining.

  • Flow cytometric analysis of A431 cells labeling Desmoglein 3/PVA with ab201968 at 1/200 dilution (green). Negative control (red).

  • All lanes : Anti-Desmoglein 3/PVA antibody [6G2C11] (ab201968) at 1/500 dilution

    Lane 1 : HEK293 cell lysate
    Lane 2 : Human Desmoglein 3/PVA recombinant (aa55-159)-hIgGFc transfected HEK293 cell lysate

    Predicted band size: 108 kDa

  • Anti-Desmoglein 3/PVA antibody [6G2C11] (ab201968) at 1/500 dilution + Human Desmoglein 3/PVA recombinant (aa55-159) protein

    Predicted band size: 108 kDa



    (Expected MW is 37.5 kDa)

References

ab201968 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab201968.
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