Overview

  • Product name

    Anti-Desmoglein 3/PVA antibody - N-terminal
    See all Desmoglein 3/PVA primary antibodies
  • Description

    Rabbit polyclonal to Desmoglein 3/PVA - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Desmoglein 3/PVA (N terminal). The exact sequence is proprietary. (Carrier-protein conjugated).
    Database link: P32926

  • Positive control

    • WB: A431 whole cell extract. IP: A431 whole cell extract.
  • General notes

    Previously labelled as Desmoglein 3. 

Properties

Applications

Our Abpromise guarantee covers the use of ab228726 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 108 kDa.
IP 1/100 - 1/500.

Target

  • Function

    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • Tissue specificity

    Epidermis, tongue, tonsil, esophagus and carcinomas.
  • Sequence similarities

    Contains 4 cadherin domains.
  • Domain

    Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
  • Cellular localization

    Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • 130 kD pemphigus vulgaris antigen antibody
    • 130 kDa pemphigus vulgaris antigen antibody
    • Balding antibody
    • Cadherin family member 6 antibody
    • CDHF 6 antibody
    • CDHF6 antibody
    • Desmoglein 3 antibody
    • Desmoglein 3 precursor antibody
    • Desmoglein-3 antibody
    • Desmoglein3 antibody
    • DKFZp686P23184 antibody
    • DSG 3 antibody
    • DSG3 antibody
    • DSG3_HUMAN antibody
    • Pemphigus vulgaris antigen antibody
    • PVA antibody
    see all

Images

  • Anti-Desmoglein 3/PVA antibody - N-terminal (ab228726) at 1/1000 dilution + A431 (human epidermoid carcinoma cell line) whole cell extract at 30 µg

    Predicted band size: 108 kDa



    7.5% SDS-PAGE gel.

  • Desmoglein 3/PVA was immunoprecipitated from A431 (human epidermoid carcinoma cell line) whole cell extract with 5 µg ab228726. Western blot was performed from the immunoprecipitate using ab228726. Anti-Rabbit IgG was used as a secondary reagent.

    Lane 1: A431 whole cell extract.
    Lane 2: Control IgG IP in A431 whole cell extract.
    Lane 3: ab228726 IP in A431 whole cell extract.

References

ab228726 has not yet been referenced specifically in any publications.

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