Overview

  • Product name

    Desmopressin, Vasopressin analog
  • Description

    Synthetic vasopressin analog
  • Biological description

    Synthetic vasopressin analog. V1B and V2 receptor agonist (EC50= 11.4 and 23.9 nM respectively). Antidiuretic, antiproliferative, hemostatic and hypotensive activity in vivo.
  • Purity

    > 95%
  • CAS Number

    16679-58-6
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    1069.10
  • Molecular formula

    C46H64N14O12S2
  • Sequence

    XYFQNCPRG (Modifications: C-terminal amide; X-1 = Mpr; Arg-8 = D-Arg; Cyclised: 1-6)
  • PubChem identifier

    27991
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bogolepova AE & Zaitseva KV [Comparative analysis of 1-desamino-arginine-vasotocin, 1-desamino-1-monocarba-arginine-vasotocin and desmopressin antidiuretic effect in rats]. Ross Fiziol Zh Im I M Sechenova 94:1191-4 (2008). Read more (PubMed: 19065832) »
  • Zubairov DM  et al. Study of the mechanism of hemostatic effect of desmopressin. Bull Exp Biol Med 144:200-2 (2007). Read more (PubMed: 18399279) »
  • Saito M  et al. 1-desamino-8-D-arginine vasopressin (DDAVP) as an agonist on V1b vasopressin receptor. Biochem Pharmacol 53:1711-7 (1997). Read more (PubMed: 9264324) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142281.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up