DETA-NONOate, Nitric oxide donor (ab144627)

Overview

  • Product name

    DETA-NONOate, Nitric oxide donor
  • Description

    Nitric oxide donor
  • Alternative names

    • NOC-18
  • Biological description

    Nitric oxide donor. Able to spontaneously release NO (t1/2 = 20 h). Also releases HNO. Decomposition is dependent on pH. Vasodilatory effects in vitro and in vivo. Cell-permeable.
  • Purity

    > 98%
  • CAS Number

    146724-94-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (Z)-1-[N-(2-Aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
  • Molecular weight

    163.18
  • Molecular formula

    C4H13N5O2
  • PubChem identifier

    1606
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Soluble in water
  • Handling

    Unstable; make up solutions fresh and use immediately.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C(CN(CCN)N(N=O)O)N
  • Source

    Synthetic

References

This product has been referenced in:

  • Kielbik M  et al. Nitric oxide donors: spermine/NO and diethylenetriamine/NO induce ovarian cancer cell death and affect STAT3 and AKT signaling proteins. Nitric Oxide 35:93-109 (2013). Read more (PubMed: 24055735) »
  • Salmon DJ  et al. HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH. Inorg Chem 50:3262-70 (2011). Read more (PubMed: 21405089) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab144627.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up