Product nameAnti-Dexamethasone antibody
DescriptionRabbit polyclonal to Dexamethasone
SpecificityCross reactivity: Dexamethasone 100%, Dexamethasone-21-Phosphate <0.01%, Dexamethasone-21-Ac 29%, Beta-Methasone 0.1%, Testosterone <0.01%.
Tested applicationsSuitable for: ELISA, Flow Cyt, ICC/IF, IHC-Frmore details
Chemical/ Small Molecule: Dexamethasone conjugated to BSA.
- Dexamethasone-thyroglobulin (2µg/ml) conjugate can be used for plate coating.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
Purification notesThis antibody was purified by ammonium sulphate fractionation.
Our Abpromise guarantee covers the use of ab35000 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||1/1000 - 1/4000.|
|Flow Cyt||Use at an assay dependent concentration. PubMed: 22643864
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use at an assay dependent concentration. PubMed: 22643864|
|IHC-Fr||Use at an assay dependent concentration. PubMed: 23663237|
RelevanceDexamethasone is potent glucocorticoid anti-inflammatory agent which regulates T-cell survival, growth and differentiation. It is known by various trivial and systematic names including 9-alpha fluoro 16-alpha methylprednisolone. Dexamethasone is also used as an inducer of gene expression using a dexamethasone-inducible promoter system. In horse racing Dexamethasone is one of many steroids drugs which are prohibited but is commonly used in racing stables as a treatment for respiratory complaints.
This product has been referenced in:
- Yang KJ et al. Optimized phospholipid-based nanoparticles for inner ear drug delivery and therapy. Biomaterials 171:133-143 (2018). IHC-P ; Mouse . Read more (PubMed: 29689410) »
- Grewal AS et al. Dexamethasone uptake in the murine organ of Corti with transtympanic versus systemic administration. J Otolaryngol Head Neck Surg 42:19 (2013). IHC-Fr . Read more (PubMed: 23663237) »