Overview

  • Product name

    Dexamethasone sodium phosphate, glucocorticoid receptor agonist
  • Description

    Potent glucocorticoid receptor agonist. Dexamethasone prodrug.
  • Biological description

    Potent glucocorticoid receptor agonist and dexamethasone prodrug (ab120743). Multiple effects on cell survival, cell signaling and gene expression. Anti-inflammatory and immunosupressant. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    2392-39-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Löwenberg M  et al. Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands. Steroids 73:1025-9 (2008). Read more (PubMed: 18221974) »
  • Samtani MN & Jusko WJ Stability of dexamethasone sodium phosphate in rat plasma. Int J Pharm 301:262-6 (2005). Read more (PubMed: 16054309) »
  • Kroin JS  et al. Chronic intrathecal administration of dexamethasone sodium phosphate: pharmacokinetics and neurotoxicity in an animal model. Neurosurgery 46:178-82; discussion 182-3 (2000). Read more (PubMed: 10626948) »

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