Overview

  • Product name
    Anti-Dexras1 antibody - C-terminal
    See all Dexras1 primary antibodies
  • Description
    Rabbit polyclonal to Dexras1 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human Dexras1 aa 247-278 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9Y272

  • Positive control
    • Mouse liver tissue lysate; Human heart tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab171370 is purified through a Protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 32 kDa.

Target

  • Function
    Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
  • Tissue specificity
    Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
  • Sequence similarities
    Belongs to the small GTPase superfamily. RasD family.
  • Post-translational
    modifications
    S-nitrosylation stimulates guanine-nucleotide exchange activity.
  • Cellular localization
    Cell membrane. Cytoplasm > perinuclear region. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activator of G protein signaling 1 antibody
    • Activator of G protein signaling antibody
    • Activator of G-protein signaling 1 antibody
    • AGS 1 antibody
    • AGS1 antibody
    • Dexamethasone induced ras related protein 1 antibody
    • Dexamethasone-induced ras protein 1 antibody
    • Dexamethasone-induced Ras-related protein 1 antibody
    • Dexras 1 antibody
    • MGC:26290 antibody
    • RAS dexamethasone induced 1 antibody
    • Ras protein, Dexamethasone-induced, 1 antibody
    • Ras related protein antibody
    • RASD 1 antibody
    • Rasd1 antibody
    • RASD1_HUMAN antibody
    see all

Images

  • Anti-Dexras1 antibody - C-terminal (ab171370) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size: 32 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling Dexras1 with ab171370 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

This product has been referenced in:
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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