Overview

  • Product name
  • Description
    Rabbit polyclonal to DFFB/CAD
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Mouse DFFB/CAD aa 205-222.
    Database link: O76075
    (Peptide available as ab8433)

  • Positive control
    • Murine kidney tissue lysate. A 40 kDaband should be detected.
  • General notes

    CAD stands for caspase activated deoxyribonuclease

    Product previously known as Anti-DFFB antibody

     

Properties

Applications

Our Abpromise guarantee covers the use of ab8401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 39 kDa.Can be blocked with Mouse DFFB/CAD peptide (ab8433).
IHC-P Use a concentration of 2 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
  • Sequence similarities
    Contains 1 CIDE-N domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAD antibody
    • Caspase activated deoxyribonuclease antibody
    • Caspase activated DNase antibody
    • Caspase activated nuclease antibody
    • Caspase-activated deoxyribonuclease antibody
    • Caspase-activated DNase antibody
    • Caspase-activated nuclease antibody
    • CPAN antibody
    • Deoxyribonuclease III, caspase activated antibody
    • DFF 40 antibody
    • DFF-40 antibody
    • DFF2 antibody
    • DFF40 antibody
    • Dffb antibody
    • DFFB_HUMAN antibody
    • Didff antibody
    • DNA fragmentation factor 40 kDa subunit antibody
    • DNA fragmentation factor subunit beta antibody
    • DNA fragmentation factor, 40 Da, beta polypeptide (caspase activated DNase) antibody
    • DNA fragmentation factor, 40 kD beta subunit antibody
    • DNA fragmentation factor, 40 kD, beta polypeptide antibody
    • DNA fragmentation factor, 40kDa, beta polypeptide (caspase activated DNase) antibody
    • OTTHUMP00000003633 antibody
    see all

Images

  • Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse kidney tissue labeling DFFB/CAD with Anti-DFFB/CAD antibody (ab8401) at 5μg/ml.

  • Anti-DFFB/CAD antibody (ab8401) at 2 µg/ml + murine kidney tissue lysate

    Predicted band size: 39 kDa

  • ab8401 at 2µg/ml staining DFFB/CAD in mouse kidney tissue by IHC

  • Immunofluorescence of DFFB/CAD in Mouse Kidney cells using ab8401 at 10 ug/ml.

References

ab8401 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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