Overview

  • Product name

  • Description

    Rabbit polyclonal to DHRS4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human
  • Immunogen

    Synthetic peptide within Mouse DHRS4 aa 51-100 (internal sequence). The exact sequence is proprietary. NP_109611
    Sequence:

    RRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKL


    Database link: Q99LB2

  • Positive control

    • Mouse heart lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab177372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 30 kDa.

Target

  • Function

    Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.
  • Tissue specificity

    Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
  • Sequence similarities

    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization

    Peroxisome. Isoform 1 is peroxisomal, while isoform 4 is not.
  • Information by UniProt
  • Database links

  • Alternative names

    • AI043103 antibody
    • AI790593 antibody
    • Carbonyl reductase antibody
    • CR antibody
    • D14Ucla2 antibody
    • Dehydrogenase/reductase SDR family member 4 antibody
    • Dhrs4 antibody
    • DHRS4_HUMAN antibody
    • humNRDR antibody
    • mouNRDR antibody
    • NADPH dependent carbonyl reductase/NADP retinol dehydrogenase antibody
    • NADPH dependent retinol dehydrogenase/reductase antibody
    • NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase antibody
    • NADPH-dependent retinol dehydrogenase/reductase antibody
    • NDRD antibody
    • NRDR antibody
    • Peroxisomal short chain alcohol dehydrogenase antibody
    • Peroxisomal short-chain alcohol dehydrogenase antibody
    • PHCR antibody
    • PRO1800 antibody
    • PSCD antibody
    • RRD antibody
    • SCAD-SRL antibody
    • SCADSRL antibody
    • Short chain dehydrogenase/reductase family member 4 antibody
    • Short-chain dehydrogenase/reductase family member 4 antibody
    • UNQ851 antibody
    see all

Images

  • Anti-DHRS4 antibody (ab177372) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size: 30 kDa

References

ab177372 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab177372.
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