Overview

  • Product name

    Diallyl tetrasulfide, ROS inducer
  • Description

    JNK activator. ROS inducer.
  • Biological description

    JNK activator. ROS inducer. Irreversible Cdc25 isoforms A and C inhibitor. Targets tubulin. Induces G2-M arrest and apoptosis. Shows antiproliferative, cytoprotective and antioxidant effects in vivo. Orally active.
  • Purity

    > 90%
  • CAS Number

    2444-49-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Saidu NE  et al. Comparison between the effects of diallyl tetrasulfide on human retina pigment epithelial cells (ARPE-19) and HCT116 cells. Biochim Biophys Acta 1830:5267-76 (2013). Read more (PubMed: 23948592) »
  • Kelkel M  et al. ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis. Carcinogenesis 33:2162-71 (2012). Read more (PubMed: 22822094) »
  • Ponnusamy M & Pari L Protective role of diallyl tetrasulfide on cadmium-induced testicular damage in adult rats: a biochemical and histological study. Toxicol Ind Health 27:407-16 (2011). Read more (PubMed: 21245201) »
See 1 Publication for this product

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