Overview

  • Product name

    Dibutyryl-cGMP, cGMP analog
  • Description

    Cell-permeable cGMP analog
  • Biological description

    Cell-permeable cGMP analog. Activates Protein Kinase G (PKG). Raises intracellular Ca2+ concentrations similar to 8-Br-cGMP (ab141449). Shows antinociceptive effects in vivo.
  • Purity

    > 96%
  • CAS Number

    51116-00-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Alves DP  et al. Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP. Eur J Pharmacol 489:59-65 (2004). Read more (PubMed: 15063156) »
  • Sato M & Kawatani M Dibutyryl cGMP raises cytosolic concentrations of Ca2+ in cultured nodose ganglion neurons of the rabbit. Brain Res 813:203-6 (1998). Read more (PubMed: 9824699) »
  • Willmott NJ  et al. Calcium store depletion potentiates a phosphodiesterase inhibitor- and dibutyryl cGMP-evoked calcium influx in rat pituitary GH3 cells. FEBS Lett 386:39-42 (1996). Read more (PubMed: 8635599) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab145203.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up