Diclofenac diethylamine, analgesic agent (ab145703)

Overview

  • Product name

    Diclofenac diethylamine, analgesic agent
  • Description

    Non-steroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic.
  • Alternative names

    • DDEA
    • Diclofenac (diethylamine)
    • Diclofenacdiethylamine
    • n-ethylethanaminium{2-[(2,6-dichlorophenyl)amino]phenyl}acetate
    • Voltaren
    see all
  • Biological description

    Non-steroidal anti-inflammatory drug. Non-selective COX inhibitor. Inhibits leukocyte migration. Exhibits bacteriostatic activity by inhibiting bacterial DNA synthesis.

  • Purity

    > 99%
  • CAS Number

    78213-16-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[2-(2,6-Dichloroanilino)phenyl]acetic acid diethylamine salt
  • Molecular weight

    369.29
  • Molecular formula

    C14H11Cl2NO2.C4H11N
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Altman R  et al. Advances in NSAID development: evolution of diclofenac products using pharmaceutical technology. Drugs 75:859-77 (2015). Read more (PubMed: 25963327) »
  • Paskauskas S  et al. Blockade of leukocyte haptokinesis and haptotaxis by ketoprofen, diclofenac and SC-560. BMC Immunol 12:64 (2011). Read more (PubMed: 22078067) »
  • Niethard FU  et al. Efficacy of topical diclofenac diethylamine gel in osteoarthritis of the knee. J Rheumatol 32:2384-92 (2005). Read more (PubMed: 16331769) »
  • Dastidar SG  et al. The anti-bacterial action of diclofenac shown by inhibition of DNA synthesis. Int J Antimicrob Agents 14:249-51 (2000). Read more (PubMed: 10773497) »

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