Overview

  • Product name

    Diethylstilbestrol (Stilbestrol), ERalpha/ERbeta dual agonist
  • Description

    Synthetic nonsteroidal ERα/ERβ dual agonist
  • Biological description

    Synthetic nonsteroidal ERα/ERβ dual agonist. Induces apoptosis in hormone-insensitive prostate cancer cells. Orally active.
  • Purity

    > 98%
  • CAS Number

    56-53-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Walker VR  et al. Estrogen receptor-a mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice. Environ Health Perspect 120:560-5 (2012). Read more (PubMed: 22275727) »
  • Ohta R  et al. Delayed reproductive dysfunction in female rats induced by early life exposure to low-dose diethylstilbestrol. Reprod Toxicol 34:323-30 (2012). Read more (PubMed: 22569274) »
  • Callard GV  et al. Evolutionary origins of the estrogen signaling system: insights from amphioxus. J Steroid Biochem Mol Biol 127:176-88 (2011). Read more (PubMed: 21514383) »
  • Folmar LC  et al. A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro. Aquat Toxicol 60:101-10 (2002). Read more (PubMed: 12204590) »
  • Robertson CN  et al. Induction of apoptosis by diethylstilbestrol in hormone-insensitive prostate cancer cells. J Natl Cancer Inst 88:908-17 (1996). Read more (PubMed: 8656443) »

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