Digitonin, detergent for solubilizing receptors and cellular membranes (ab141501)

Overview

  • Product name

    Digitonin, detergent for solubilizing receptors and cellular membranes
  • Description

    Detergent for solubilizing receptors and cellular membranes
  • Biological description

    Non-ionic detergent. Able to solubilize receptors and permeabilize cellular and nuclear membranes.
  • CAS Number

    11024-24-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (25R)-2-α,15-β-Dihydroxy-5-α-spirostan-3-β-yl β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside

  • Molecular weight

    1229.31
  • Molecular formula

    C56H92O29
  • PubChem identifier

    16219213
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 25 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Toxic, refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1CCC2(C(C3C(O2)C(C4C3(CCC5C4CCC6C5(CC(C(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)OC9C(C(C(CO9)O)O)O)OC2C(C(C(C(O2)CO)O)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O)C)C)O)C)OC1
  • Source

    Digitalis purpurea

  • Research areas

References

This product has been referenced in:

  • Geelen MJ The use of digitonin-permeabilized mammalian cells for measuring enzyme activities in the course of studies on lipid metabolism. Anal Biochem 347:1-9 (2005). Read more (PubMed: 16291302) »
  • Liu J  et al. Use of digitonin-permeabilized cells in studies of steroid receptor subnuclear trafficking. Methods 19:403-9 (1999). Read more (PubMed: 10579935) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141501.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up