Key features and details
- Detergent for solubilizing receptors and cellular membranes
- CAS Number: 11024-24-1
- Soluble in water to 25 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Digitalis purpurea
Product nameDigitonin, detergent for solubilizing receptors and cellular membranes
DescriptionDetergent for solubilizing receptors and cellular membranes
Non-ionic detergent. Able to solubilize receptors and permeabilize cellular and nuclear membranes.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 25 mM and in ethanol to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141501 has been referenced in 4 publications.
- Li Y et al. Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals. Elife 8:N/A (2019). PubMed: 31021318
- Goodnight AV et al. Chromatin accessibility and transcription dynamics during in vitro astrocyte differentiation of Huntington's Disease Monkey pluripotent stem cells. Epigenetics Chromatin 12:67 (2019). PubMed: 31722751
- Shen Y et al. Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G2/M-phase transition. J Biol Chem 293:5185-5199 (2018). PubMed: 29467227
- Ying L et al. Mitofusin 2 Promotes Apoptosis of CD4+T Cells by Inhibiting Autophagy in Sepsis. Mediators Inflamm 2017:4926205 (2017). PubMed: 29358849