Dihomo-gamma-linolenic acid (20:3, n-6), Long-chain polyunsaturated fatty acid (ab145213)

Overview

  • Product name

    Dihomo-gamma-linolenic acid (20:3, n-6), Long-chain polyunsaturated fatty acid
  • Description

    Long-chain polyunsaturated fatty acid
  • Biological description

    Long-chain polyunsaturated fatty acid. Cyclooxygenase and lipoxygenase substrate (IC50 =45 μM, LTB4 formation). Biosynthetic PGE1 precursor. Elongase product of γ-linolenic acid (ab145168). Arachidonic acid (ab120916) analog. Energy source in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    1783-84-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Huang YS  et al. Eicosadienoic acid differentially modulates production of pro-inflammatory modulators in murine macrophages. Mol Cell Biochem 358:85-94 (2011). Read more (PubMed: 21688154) »
  • Iversen L  et al. Effect of dihomogammalinolenic acid and its 15-lipoxygenase metabolite on eicosanoid metabolism by human mononuclear leukocytes in vitro: selective inhibition of the 5-lipoxygenase pathway. Arch Dermatol Res 284:222-6 (1992). Read more (PubMed: 1329675) »
  • Hassam AG & Crawford The effect of dihomo-gamma-linolenic acid (20: 3,n-6) on the composition of phospholipid fatty acids in the liver of rats deficient in essential fatty acids. Br J Nutr 40:155-7 (1978). Read more (PubMed: 666999) »

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