Dimethoxycurcumin, curcumin analog (ab144440)
Key features and details
- Metabolically more stable curcumin analog. Antiproliferative agent.
- CAS Number: 160096-59-3
- Purity: > 90%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dimethoxycurcumin, curcumin analog -
Description
Metabolically more stable curcumin analog. Antiproliferative agent. -
Biological description
Metabolically more stable curcumin (ab120618, ab141921) analog. Antiproliferative agent. Induces non-cytotoxic G2/M phase cell cycle arrest and apoptosis. Induces the expression of promoter methylated genes. Inhibits NO production, iNOS expression and NF-κB activation. Shows antiproliferative effects (IC50 = 0.5-1 μM). -
Purity
> 90% -
CAS Number
160096-59-3 -
Chemical structure
Properties
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Chemical name
(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione -
Molecular weight
396.44 -
Molecular formula
C23H24O6 -
PubChem identifier
9952605 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C(C=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)OC)OC)OC -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab144440 has not yet been referenced specifically in any publications.
