Overview

  • Product name

    Dimethyl Fumarate, anti-inflammatory agent
  • Description

    Anti-inflammatory agent
  • Biological description

    Anti-inflammatory agent. Potentiates cellular resistance to oxidative damage. HCA2 agonist. Up-regulates the Nrf2. Depletes intracellular glutathione. Shows neuroprotective effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    624-49-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Chen H  et al. Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE. J Clin Invest : (2014). Read more (PubMed: 24691444) »
  • Scannevin RH  et al. Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway. J Pharmacol Exp Ther 341:274-84 (2012). Read more (PubMed: 22267202) »
  • Held KD  et al. Effect of dimethyl fumarate on the radiation sensitivity of mammalian cells in vitro. Radiat Res 115:495-502 (1988). Read more (PubMed: 3174933) »

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