Overview

  • Product name
    Anti-DIO1 antibody - N-terminal
  • Description
    Rabbit polyclonal to DIO1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human DIO1 aa 36-66 (N terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P49895

  • Positive control
    • WB: HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab175973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.

Target

  • Function
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
  • Sequence similarities
    Belongs to the iodothyronine deiodinase family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5DI antibody
    • deiodinase iodothyronine type I antibody
    • DIO1 antibody
    • DIOI antibody
    • IOD1 antibody
    • IOD1_HUMAN antibody
    • thyroxine deiodinase type I (selenoprotein) antibody
    • TXDI1 antibody
    • Type 1 DI antibody
    • type I 5' deiodinase antibody
    • Type I iodothyronine deiodinase antibody
    • Type-I 5''-deiodinase antibody
    see all

Images

  • Anti-DIO1 antibody - N-terminal (ab175973) at 1/1000 dilution + HepG2 cell lysate at 35 µg

    Predicted band size: 29 kDa

References

ab175973 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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