Overview

  • Product name

    Diosmetin, human CYP1A enzyme activity inhibitor
  • Description

    Human CYP1A enzyme activity inhibitor
  • Biological description

    Human CYP1A enzyme activity inhibitor. A natural flavonoid that has anti-mutagenic and anti-allergic characteristics in vitro. Inhibits tumor growth and protect tumor-induced apoptosis in vivo.
  • Purity

    > 98%
  • CAS Number

    520-34-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
  • Molecular weight

    300.26
  • Molecular formula

    C16H12O6
  • PubChem identifier

    5281612
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
  • Source

    Vicia sp.

  • Research areas

References

This product has been referenced in:

  • Zhao R  et al. Protective effects of diosmetin extracted from Galium verum L. on the thymus of U14-bearing mice. Can J Physiol Pharmacol 89:665-73 (2011). Read more (PubMed: 21851214) »
  • Cheong H  et al. Studies of structure activity relationship of flavonoids for the anti-allergic actions. Arch Pharm Res 21:478-80 (1998). Read more (PubMed: 9875480) »
  • Villa P  et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology 73:179-89 (1992). Read more (PubMed: 1609428) »
See 1 Publication for this product

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