Overview

  • Product name

    Diosmin, antitumor agent
  • Description

    Anti-inflammatory, antioxidant and antitumor agent
  • Biological description

    Anti-inflammatory, antioxidant and antitumor agent. Potentiates SOD, catalase and glutathione peroxidase activity. Anti-ischemic effects in vivo. Orally active.
  • Purity

    > 95%
  • CAS Number

    520-27-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
  • Molecular weight

    608.54
  • Molecular formula

    C28H32O15
  • PubChem identifier

    5281613
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM (with warming) and in DMSO to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Tahir M  et al. Diosmin protects against ethanol-induced hepatic injury via alleviation of inflammation and regulation of TNF-a and NF-?B activation. Alcohol 47:131-9 (2013). Read more (PubMed: 23419394) »
  • Tong N  et al. Diosmin protects rat retina from ischemia/reperfusion injury. J Ocul Pharmacol Ther 28:459-66 (2012). Read more (PubMed: 22509733) »
  • Abdel-Salam OM  et al. Neuroprotective and hepatoprotective effects of micronized purified flavonoid fraction (Daflon®) in lipopolysaccharide-treated rats. Drug Discov Ther 6:306-14 (2012). Read more (PubMed: 23337818) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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