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Rabbit polyclonal to DIP13B
HumanPredicted to work with:
Mouse, Rat, Cow, Xenopus laevis, Xenopus tropicalis
Recombinant fragment, corresponding to a region within amino acids 1-225 of Human DIP13B (Uniprot ID: Q8NEU8).
- NT2D1, IMR32 whole cell lysate
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/3000. Predicted molecular weight: 74 kDa.
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
High levels in brain, heart, kidney and skeletal muscle.
Involvement in disease
Note=A chromosomal aberration involving APPL2/DIP13B is found in patients with chromosome 22q13.3 deletion syndrome. Translocation t(12;22)(q24.1;q13.3) with SHANK3/PSAP2.
Contains 1 PH domain.
Contains 1 PID domain.
Early endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Information by UniProt
- Adapter protein containing PH domain antibody
- Adapter protein containing PH domain PTB domain and leucine zipper motif 2 antibody
- adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"