Overview

  • Product name

    Anti-Diphtheria Toxin antibody [11D9]
    See all Diphtheria Toxin primary antibodies
  • Description

    Mouse monoclonal [11D9] to Diphtheria Toxin
  • Host species

    Mouse
  • Specificity

    ab53827 reacts primarily with Diphtheria toxin with a low cross reactivity with Diphtheria toxoid (formaldehyde-inactivated Diphtheria toxin).
  • Tested applications

    Suitable for: WB, ELISA, Conjugationmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Diphtheria toxoid (formaldehyde inactivated Diphtheria toxin).

  • General notes

    For a recombinant antibody to Diphtheria Toxin, please see - ab209329.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Constituents: 2.9% Sodium chloride, 0.0268% PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    11D9
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 63 kDa (predicted molecular weight: 58 kDa). 63kDa band corresponds to the proenzyme.
ELISA Use at an assay dependent dilution.
Conjugation Use at an assay dependent dilution.

Target

  • Relevance

    Corynebacterium diphtheriae is a gram-positive, nonmotile bacteria found in soil and animal feces. C. diphteriae infect the epithelial cells of the upper respiratory tract from where they produce and secrete a potent toxin. This toxin is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body.
  • Cellular localization

    Secreted
  • Alternative names

    • Corynebacterium diphtheriae toxoid antibody
    • Diphtheria Toxin antibody
    • tox antibody

References

This product has been referenced in:

  • Jalah R  et al. Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers. Bioconjug Chem 26:1041-53 (2015). ELISA ; Mouse . Read more (PubMed: 25970207) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for contacting Abcam.
We have not mapped the exact epitope that ab53827 binds too and so I am unable to let you know whether it does bind within amino acids 1-389 or not.
I am sorry that I am unable to provide anymore information for you on this matter, but please let me know if there is anything else I can help you with.

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