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Could you tell me whether you have mapped the binding epitope for these antibodies?
Asked on Jan 10 2014
This anti-Diphtheria toxin antibody is a polyclonal raised against the whole Diphtheria toxin. Thus the product likely contains antibodies that bind epitopes found within the catalytic domain and translocation domain. This antibody is known to neutralize toxin activity and this is thought to occur due to antibody binding to the catalytic domain.
Jeremy KasanovAbcam Scientific Support
Answered on Jan 10 2014