Overview

  • Product name

    Diprotin A, Dipeptidyl peptidase IV inhibitor
  • Description

    Dipeptidyl peptidase IV inhibitor
  • Biological description

    Dipeptidyl peptidase IV inhibitor. Diprotin B (ab145600) analog. Shows antihyperglycemic and analgesic effects in vivo. Centrally active.
  • Purity

    > 98%
  • CAS Number

    90614-48-5
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    341.45
  • Molecular formula

    C17H31N3O4
  • Sequence

    IPI
  • PubChem identifier

    94701
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC[C@H](C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)O)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chakraborty C  et al. Understanding the molecular dynamics of type-2 diabetes drug target DPP-4 and its interaction with Sitagliptin and inhibitor Diprotin-A. Cell Biochem Biophys 70:907-22 (2014). Read more (PubMed: 24809328) »
  • Hiramatsu H  et al. The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A. Biol Chem 385:561-4 (2004). Read more (PubMed: 15255191) »
  • Rónai AZ  et al. Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV(EC 3.4.14.5) produces naloxone-reversible analgesia in rats. Life Sci 64:145-52 (1999). Read more (PubMed: 10069492) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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