Product nameDiR near-IR membrane probe
Lipophilic near-IR (NIR) fluorescent membrane probe.
Biological Description:This tricarbocyanine fluorophore is excited at 750 nmand has an emission peak at 782 nm. It also has virtually no fluorescence in water, while having high fluorescence when incorporated into cell membranes. Long-chain dialkylcarbocyanines are widely used as anterograde and retrograde neuronal tracers in living and fixed tissues and cells.
Chemical name: 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide
Molecular Formula: C63H101N2I
Molecular Weight: 1013.39
Storage: -20oC, desiccated, protect from light
Solubility: CHCl3, MeOH
Tested applicationsSuitable for: Othermore details
Our Abpromise guarantee covers the use of ab189810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Other||Use at an assay dependent concentration.
Staining membrane with near IR emission
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab189810 has been referenced in 4 publications.
- Partain BD et al. The clearance and biodistribution of magnetic composite nanoparticles in healthy and osteoarthritic rat knees. J Control Release 321:259-271 (2020). PubMed: 32004585
- Dos Santos Rodrigues B et al. Dual functionalized liposome-mediated gene delivery across triple co-culture blood brain barrier model and specific in vivo neuronal transfection. J Control Release 286:264-278 (2018). PubMed: 30071253
- Yao Q et al. Building Stable MMP2-Responsive Multifunctional Polymeric Micelles by an All-in-One Polymer-Lipid Conjugate for Tumor-Targeted Intracellular Drug Delivery. ACS Appl Mater Interfaces 9:32520-32533 (2017). PubMed: 28870072
- Yao Q et al. Improving Tumor Specificity and Anticancer Activity of Dasatinib by Dual-Targeted Polymeric Micelles. ACS Appl Mater Interfaces 9:36642-36654 (2017). PubMed: 28960955