Description

Associated products

Specifications

Our Abpromise guarantee covers the use of ab191381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Dishevelled 3 antibody [EP1991Y] (ab76081)

  • Form

    Liquid
  • Additional notes

    This is an immunizing peptide for ab76081.

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C.

General Info

  • Alternative names

    • Dishevelled 3
    • Dishevelled 3 (homologous to Drosophila dsh)
    • Dishevelled 3, dsh homolog (Drosophila)
    • Dishevelled, dsh homolog 3 (Drosophila)
    • Dishevelled-3
    • DSH homolog 3
    • dvl3
    • DVL3_HUMAN
    • KIAA0208
    • OTTHUMP00000210777
    • OTTHUMP00000210778
    • Segment polarity protein dishevelled homolog DVL 3
    • Segment polarity protein dishevelled homolog DVL-3
    see all
  • Function

    May play a role in the signal transduction pathway mediated by multiple Wnt genes.
  • Sequence similarities

    Belongs to the DSH family.
    Contains 1 DEP domain.
    Contains 1 DIX domain.
    Contains 1 PDZ (DHR) domain.
  • Post-translational
    modifications

    Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

References

ab191381 has not yet been referenced specifically in any publications.

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